Wizard Pro is a multivariate statistics program for data analysis and exploration. The software keeps all work (tables, results, predictions) in a single document with an iTunes-like navigator and provides interactive interfaces for querying data. It includes basic statistics tests, regression models and results, stacking and joining of tables, indicator variables with custom logic, import of XLS, CSV, and tab-delimited files, import/export of Stata, SPSS, and R files, export of models as Stata, SPSS, and R commands, and more.
If you don't need all this power, check out Wizard, Wizard Pro's little brother.
Note: The downloadable demo is version 1.9.45; the version available for purchase on the Mac App Store is version 1.9.49.