Get professional scans from prints, negatives, and transparencies at whatever resolution and bit depth your scanner can handle. This is the best I have worked with in this price range. The next step up should be Silverscan for much more money however, I cannot see any difference in the scan quality. Also, the developer Ed Hamrick, works on this program all the time, adding new scanners and making improvements. I have been using this program for years. My only complaint is that it does not keep the pre-scan in memory, so for scanning multiple slides or negatives you need to do a time-consuming pre-scan after every scan. That is one of the only obvious advantages of Silverscan over VueScan for my work.