Geneious Prime
Geneious Prime


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Geneious Prime free download for Mac

Geneious Prime2020.2.1

15 July 2020

Sequence analysis software for molecular biologists.


Geneious Prime combines all the major DNA and protein sequence analysis tools into one application.

  • Sequence alignment
  • Contig assembly
  • Primers
  • Cloning
  • Restriction analysis
  • Phylogenetics
  • Automatic publication updates

The quoted price is that for a subscription version license good for 1-year for non-commercial use. The pricing schema can be found here.

What's new in Geneious Prime

Version 2020.2.1:
  • Alignment View: Fixed partial CDS extraction producing a sequence with a frame shifted translation
  • Analyze CRISPR Editing Results: Fixed crash on some data sets and improved handling of Sanger data
  • Batch Restriction Cloning Workflow: Workflow updated to use the modern restriction cloning operation
  • Find in Document: Fixed so that it works on "Text View" and is not wrongly disabled sometimes on "Annotations" view
  • Genbank Export: Moved option to include restriction sites as features to Advanced Preference
  • Genbank Import: Prevent importing of invalid primer annotations
  • Global Search:
    • Fixed errors with non-alphanumeric characters in the search query
    • Improved result sorting
  • Import BLAST XML: Fixed crash when importing BLAST results from XML files when BLAST services are disabled in
  • Creating a new database in a new directory correctly resets recently viewed items in search popup
  • Clearing search history in general preferences resets recently viewed items in search popup
  • New Search:
    • Optimize Codons and Analyze Silent Mutations: Reverse selection is now indicated in the options (when selecting from right to left)
    • Primer Design: Generated primers use appropriate IUPAC ambiguity code instead of N
  • Restriction Enzymes: Prevent crash during Geneious startup when an invalid enzyme file is being loaded
  • Search UI: Fixed UI rendering issue when searching multiple shared databases

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How would you rate Geneious Prime app?

5 Reviews of Geneious Prime

10 October 2011
Version: 5.5.3

Most helpful

"free" in this case means $795. Oh, well.
23 April 2012
Version: 5.6.1
it's 5.6.2
10 October 2011
Version: 5.5.3
"free" in this case means $795. Oh, well.
Show comments (3)
30 March 2011
Version: 5.4.0
Note that 5.4.0 is a beta. The current stable release is 5.3.6. Check the developer's web site for more info.
Show comment (1)
10 July 2009
Version: 4.7.1
Geneious is a superb piece of software for all molecular biologists. I love it. It saved me heaps of time.
22 August 2006
Version: 2.0.4
For a long time scientists who generate or analyse DNA sequences have been using multiple pieces of software to: 1) view chromatographs, 2) trim sequences 3) Blast data 4) align sequences 5) build phylogenetic trees. Chopping and changing between different file formats and at times different operating systems (Mac, PC, Unix/Linux) has been a frustrating and time-consuming exercise. Current and future releases of Geneious ( offer a solution to (most) of these frustrations. The software logo “research in a flash” accurately describe the potential of Geneious - only months after its release it has become the “Swiss army knife” of bioinformatics software. The user interface of Geneious is both attractive and intuitive. While the software has some “bell and whistles” for more complex tasks one of its key attributes is a simple user interface. Earlier this year I used the Beta-release in some undergraduate teaching labs - with great success. Students did a Genbank search, downloaded files, did an alignment and built a phylogenetic tree (with bootstrapping) all in the blink of an eye. If you are looking for a piece of bioinformatics software for teaching purposes look no further than Geneious. With the integration of sequence chromatograph viewing and editing of DNA sequences/alignments (new in version 2) Geneious is now firmly embedded in my research practices. As is the case with any new software there are a few features that don't work quite as well as you might like - but the good news is that if you write to them they will likely fix it up asap. My request to provide a variety of nucleotide colour schemes was implemented within 2 weeks. Moreover, the software is structured in such a way that “new” plugins can be written and incorporated with relative ease. The Geneious team has made available a freeware version and a pro version that (for a price) allows you to access more functionality. Based on the hours of time this program has saved me already I would not even blink at the academic price tag of $133 (USD) - or cheaper for students. The software almost has too many features to comment on in any one review (e.g. “agents” and collaboration modes) - the best advice I can give is to download it, do the tutorial and test drive it on a bioinformatics task that you regularly conduct - it won't disappoint. Cheers,