Lunar controls the same brightness that you can change by using the monitor's physical buttons.
It doesn't interfere at all with the native adaptive brightness that macOS implements for the built-in display
It works well along Night Shift and True Tone (and f.lux if Gamma/Software controls are not used)
Updated on Jan 19 2022
Note: if you have a monitor connected to the HDMI port of the 2021 MacBook, disable DDC manually for that monitor.