PiPifier is a native macOS 10.12 Safari extension that lets you use every HTML5 video in picture-in-picture mode.
If you have an HTML5 video playing on any website like YouTube, just press the PiPifier icon in Safari's toolbar to enable picture-in-picture for this video. Make sure you have interacted with the video player once before pressing (like play/pause).
Note: This application contains in-app and/or external module purchases.
Updated on Aug 06 2021