The game is based on a deathmatch setting, where multiple players face off in a closed level. Each player is equipped with five weapons selected from all the weapons allowed, and with a ninja rope that allows the player to move in any direction. Players begin with a set number of lives, and whilst the game records the number of kills, the last man standing is usually considered the winner. LieroX also allows team deathmatches, which has made it common for players to form clans.
Because of the huge community, there are dozens of levels and mods available. You also have no problem finding somebody on the Internet to play with. Or if you want to play offline, you also can play with bots.