It's a great concept for a program, but LocationChanger is lacking in a number of key areas. It is difficult to configure, as virtually all settings are simply text fields that must be filled in. (Growl Path? To the PrefPane? No...)
I've followed this App ver time, and frustratingly, bugs get fixed in one version and then reappear in another -- it appears it went from one developer to another, and the new group decided to reimplement a _very_ poorly considered feature. (Specifically, the danged thing turns on Network Proxies every time my Location changes. No way to stop this -- I have to manually change Network Prefs _every time_ now....)
All in all, this app would be nice if it were readily useable, but it's too hard for a layman to configure, and has recurring usability issues. If you can get it set up it can be useful, but there are alternatives that are worth the price.
I would recommend the shareware NetworkLocation instead. Fewer features (so far), but very easy to use.