I run a printing/sign company, and a newlsetter publishing company. When I started, I investigated both vertical-market data management applications and database managers for the Mac; the vertical-market apps were too restrictive in reporting and invoicing capabilities for my needs, and the Mac apps were either too weak or required too great an investment of time to achieve the results I wanted -- until I tried Helix.
With Helix, I have created accounting, order tracking, invoicing, estimating, subscription fulfillment, and a multitude of customized reports for these two companies. And when I need to make changes or add new features, the graphical interface made the task well within my capabilities.
As far as I am concerned Helix is simply the best database manager I have come across, both in terms of its power and ease of use.