Scribus is an Open-Source program that brings award-winning professional page layout to Linux/Unix, OS X, and Windows desktops with a combination of "press-ready" output and new approaches to page layout. Underneath the modern and user-friendly interface, Scribus supports professional publishing features such as CMYK color, separations, ICC color management, and versatile PDF creation. Scribus/Aqua is a port of Scribus to a native Aqua build using Qt Free for OS X.
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