Yojimbo is not the "swiss army knife" of information organizers. Its forte is text. So no video, no audio, no Pages/Keynote/Excel files.
There are other apps that do that -- Together, DEVONthink, EagleFiler, etc.
What Yojimbo excels at is text. And it EXCELS. It is fast -- LIGHTNING fast. Search is great, tagging is great, and it is outstanding for RTF, plain text, PDFs, Web Archives, bookmarks, serial numbers, and tags. I used DEVONthink for 6 years prior to switching to Yojimbo a month ago. And since I moved all my non-text documents to the Finder and tagged them, I can find them and sort/use them more easily (DEVONthink will export stuff to the Finder but it is impossible to figure out the results without opening them in DEVONthink as it changes their icons in summary).
I moved all my RTF documents to Yojimbo, and tagged them. Now browsing and searching are VERY fast, and I get one feature DEVONthink never had -- sync of notes across machines, automatically, via MobileMe. YAY! This is more useful to me than almost anything; given the convoluted workflow that involved DropBox I had before.
So, in summary, if you want a kitchen sink, this isn't the app for you. If you want a text-based information scalpel, that's Yojimbo. And after a month, I am happy to open and use it every day. DEVONthink, while powerful, was for the most part drudgery. I still use it when I want to OCR some documents, and that's about it. I don't miss it.