iTunesControl allows you to control iTunes without having to bring it to the foreground.
Ever find yourself in the middle of replying to an email, and a song comes on that you want to skip over? Instead of stopping what you're doing, bringing iTunes to the front, advancing to the next song, and then going back to what it was you were previously doing. Now just directly from within your email application! That's it!
While iTunesControl is running simple iTunes command keys are forwarded onto the iTunes application.
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If you want to control iTunes via hot key, you get iMote, ByteController, SizzilingKey and iTunesCheck. All these four applications may let you customize hot key combination, and they all have floaters to show the current track, and they are free.