Developer website: Warren Gish
WU-BLAST is the original BLAST with gapped alignments and statistics, supporting virtually unlimited size sequences and databases, with important features, speed and reliability for the power user. Gapped alignments and Sum statistics are provided in all search modes (BLASTP, BLASTN, BLASTX, TBLASTN, TBLASTX), along with segmented sequences, enhanced tabular output, XML output, and much more.
Free for academic and non-profit use.
Mac OS X or Darwin.