I found that Drive Genius can do something that TechTool Pro and Disk Warrior cannot: It can initialize a drive. I needed this recently for a thumb drive that I wanted to partition. None of my other utilities, including Disk Utility, could partition the drive, even though it was in HFS+ format. I found the initialize function in Drive Genius and, after applying it to the thumb drive, I had no trouble partitioning the drive with Disk Utility. Sadly, the partition function in Drive Genius is, shall we say, less than genius. Then again, the operation in Disk Utility is laid out differently in Sierra than in previous versions of the app so it too took some getting used to. You can no longer preselect the number of partitions. You have to add them one at a time, which hardly seems like an improvement. Just one more instance of Apple dumbing down its software, fixing something that wasn't broken to begin with. So that's not exactly genius either.
That said, it's hard to see the value proposition for the version 5 upgrade of Drive Genius. Once Apple has adopted the APSF drive format, the upgrade may be more important. But there are far cheaper malware scanners, as in free, that do the job well. Malwarebytes has worked well for me, though it doesn't run in the background as Drive Pulse does. As for Drive Pulse, I only started using it recently; it reports changes to login items that can indicate changes made by malware, though most often they are made by reliable apps you choose to use. As far as I recall, Checkmate does not do this. Whether this function is important I'm sure is a matter of opinion. Since it works in Drive Genius 4, upgrading to version 5 hardly seems essential.