can assign hotkeys to file and folders with a very easy editor. Any item that the Finder can open may be dragged to the list of AliasKeys and assigned a combination of keys, to open it without touching your mouse. You can use AliasKeys for applications, documents, folders, aliases, preference panels, servers, scripts.
Hitting the keys opens the corresponding item, as would a double-click on its icon. AliasKeys is basically as simple as that; it is also extremely easy to set up.