SEVDESTRUCT  I love Launchbar. I generally do not click on anything to get where I need to go in my system. I don't bother with the Dock stealing window space and doing it's fancy jig.

As a designer, this program saves me a lot of money by cutting down a lot menial in-between time in a process that adds up to dollars.

I got my whole studio to install it, and never do I need to fumble around wondering where photoshop is or illustrator or whatever else I need to launch on other users' machines. I just type PS or AI and bam, I'm off.

5 Stars. I use it like it's an integrated part of the system (add Launchbar to login items, and edit the .plist to remove it from the dock and cmd-tab icons)* and it's always there.

So good. Fast, and intuitive.

*There should be a note about how to do this on their site (LaunchBar) forum.  
(Version 4.3.3)

SEVDESTRUCT  I've been using Synergy Advance for a good long time, and love the Growl integration, and the level of key customization and control, but due to the lack of updates on Wincent's end for Leopard, or in general,

I've been looking for something new and so far CoverSutra has my bid. It definitely fits well into the leopard interface. The visual notifiers are great.

Only comment for amissing feature I have so far is that it'd be nice to have a hotkey to show/hide the growl display. The current player control window serves this purpose, but a bit bulky when you just want to check what track is playing, etc.  
(Version 1.2)