RAMINF I have gone through four different FTP clients (not counting the ones built into DreamWeaver and Espresso). But for copying files quickly to my server, I always go back to using ExpanDrive. Having the server be an extension of the filesystem makes it so you don't have to think about all the extra steps needed to move files back and forth. Being able to directly edit my server config files in TextEdit or add a line to a remote CSS file using CSSEdit is beyond awesome.
Haven't had any problems across any of the different hosting sites I use. Heartily recommended.
(Version 2.0.1)