POIKKEUS  This novel Safari add-on allows you to see small images of the websites you're going to visit in the margin of the frame, and also alters the behavior of Safari in certain ways. It's the kind of application that takes getting used to, but after a while you can come to depend on its time-saving features - particularly if you're using your machine on and off throughout the day.  
(Version 1.0b8)

POIKKEUS  LazyMouse is a reincarnation of the great (and free) CursorZoom, which was discontinued after Tiger took over a major feature. It's the kind of feature that should be in the Mac OS to start off with: when use the command box, the mouse quickly appears so you don't have to look for it. Ideally, we should be using key shortcuts for this kind of thing, but having the cursor handy is surprisingly useful.

Alas, CursorZoom was impressive in that the cursor "zoomed" all the way across the screen to the command box; LazyMouse is somewhat less dramatic or eye-catching. Perhaps some future version will remedy this. That said, the price is low, and for some, the convenience is well worth it.   
(Version 2.0.3)

POIKKEUS  No one player takes top honors. It's hard to ignore the advantages of VLC: flexible, free, easy to use. It accepts a wider spectrum of media (including a number that Quicktime outright rejects), and easily plays subtitles. Most of the time, I find myself using VLC, if only because you can play just about anything.

In its Pro version, Quicktime has its own special advantages. It's much more capable at audio/video editing, and significantly more stable with large files. There's a slight bump in speed, as well.

I find myself using both, but can't imagine doing my computing with only one. VLC fulfills 70% of my needs, but Quicktime (Pro) fills in the gaps . One only wishes that the latter, an essential app, could view a wider variety of content.   
(Version 7.2)

POIKKEUS  After the retirement CursorZoom, another program that performed this same task, Lazy Mouse is the only game in town when it comes this extremely useful function. Although one should normally use keyboard shortcuts, this quite addictive. As long as you stay in Safari, it's probably money spent well.

But the point is well taken - Firefox isn't covered (yet, at least), and for such a small app, it's little to ask.  
(Version 1.1.3)

POIKKEUS  From its novel registration system to the app itself, 1Password aims to write and save secure passwords as you type. It's a wonderful concept, but maybe a little less so in execution. Its success with forums varies, and negotiatng the 40+ page manual (nicely illlustrated, though) can be a chore.  
(Version 2.4.2)