PJDODD I agree with most of what has been said about Quark 7 (7.0 to 7.31), especially regarding speed and reliability. I use it sparingly on a dual G5 when work comes in from outside sources and it's painful. We only upgraded to Quark 7 because other silly people had gone that route without looking ahead and/or waiting for a stable release.
I'm also not a fan of InDesign CS3. It takes as long to load as Quark 7.31 and has it's own speed issues (loading, saving, flattening artwork). There is also a disturbing problem with Pantone colours reproducing accurately from InDesign, especially using RIPs. I liked the comment that InDesign "feels Pagemaker" and it does.
There is a lot to champion for Quark 6.5.2, especially speed and stability. It launches in a few seconds and loads and saves files very quickly. I can still crash it when activating fonts but this is also true of every version of Quark and InDesign - the technology changes but the problems with fonts stay the same.
(Version 7.31)