MAMSTER2  I'm working on producing my first podcast, and after trying many, many apps (and having a data loss nightmare with GarageBand), I've settled on Fission for cleaning up a raw recording.

Yeah, if you look at the feature list, Fission doesn't measure up to Peak or Amadeus or whatever. That's not the point. Fission is *extremely* good at what it does. Plowing through a bunch of audio and deleting boring bits and ums is about three times as fast as Garageband. Fission is smart about keeping the selection sticky but not too sticky, and the way it handles regions of audio is smarter than the marker systems in other apps. It also has great keyboard shortcuts.

This is a fun app, and I've found it to be totally stable on Snow Leopard, which is a lot more than I can say for GarageBand. Absolutely worth the price. I have zero affiliation with Rogue Amoeba and have never bought one of their products before, I just love this app.  
(Version 1.6.6)