IPHONEANDMACDEVELOPER  Just posted v5.1.1, but if that doesn't work, you need to contact me. Otherwise I can't help you. Send email to .  
(Version 5.1)

IPHONEANDMACDEVELOPER  If I search for "preference file delete" I can find a few applications that do as you request. But if none of them work, let me know and I'll develop such an application. I did many years ago, called it Yank, and it was very popular. Maybe I could update it for OS X if there was interest. Send email to me at modesittsoftware(at)me.com  
(Version 1.0)

IPHONEANDMACDEVELOPER  Yes, there is a way to indicate to the program whether the meds have been taken, and if they've been taken at a different time to what was planned. It's on the "Consumed Log" window. For every med consumed, add a log entry which contains the consumed time (which can be edited).

If multiple drugs are due at the same time the program uses multiple alarms.

The next release will allow two medications in demo mode.

Logging meds that are consumed as needed can be done, but it's not fully implemented yet.

Please contact me via email for more suggestions and comments. I don't always look here for input. Thanks.  
(Version 1.1)

IPHONEANDMACDEVELOPER  Soon there will be MedsLog for the Mac, just as there is now for the iPhone & iPod Touch. MedsLog will do reminders and more!  
(Version 1.1)