HODAGACZ I tried Crossover Mac when it first came out, and was pretty impressed. Then they released Crossover Games and it is amazing. I can run Access (not my first choice of DB) perfectly smoothly, and this is the non-Office optimized version! I haven't tried 7.x yet, but I would be very surprised if it wasn't as polished. I have used Darwine, and for personal machines where I have the spare time to fiddle with it, it's fine. However for work machines, I prefer Crossover.
(Version 7.0.2)