CYBERCAT  Many thanks to the makers of this for creating it, AND keeping it up to date! Plays great on my Mac mini, it's wonderful that this old classic is once again playable on modern operating systems. Make sure to read the readme document included with the download and follow the instructions carefully.

I ended up not being able to just copy the plain old files directly from my Descent 2 CD and instead had to actually install Descent 2 on my Windows XP machine, then copy the files from the install directory to the data folder (which you create) on my mac.

Once again, top notch!  
(Version 1.6.171)