OSS 2.0: I am running 10.4.9 (old G4 tower with 1Ghz card) with iTunes 7.0 with Monsoon 2000 speakers. Works great if you READ THE MANUAL. I created an alias in the dock as it did not appear in the iTunes top bar under "window" Have not tried with Garage Band or anything else. If you are running into a high end system, this is an excellent choice to use with iTunes. Use AppZapper to remove old copies.
[Version 2.2]
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OSS 3D