There is so many bad comments on this app that I'd like share my experience. I got this app as an extra from MuPromo bundle (Back to School). I had also trouble with the first reg code, but the second one worked just fine. I installed Kameleon, Disingenuous theme, both to System and iTunes. iTunes was prior to 8 (7.x) - I intended not to upgrade to iTunes 8.0 because all the crashing experiences people got. But - I forgot I had downloaded (but not installed) iTunes 8.0 with Software Update days before... So when I booted my MacBookPro, iTunes 8.0 got installed! I can tell you that I was really surprised that everything still worked just fine - even iTunes 8.0. Actually new Kameleon skin looks very nice! I don't know what causes the crashing problem all the other people got, but mine works flawlessly. Maybe it's that I installed Kameleon first and iTunes 8.0 (34) after that. I have a myriad of other programs installed and started at login, so it's not a question of "clean" system - far from that. ;-) I have Leopard 10.5.4. I suggest that the developer of Kameleon should check the installation issues if there's something wrong with that...
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All I want to say is, that Kameleon works just fine with iTunes 8.0 - if the right conditions (?) are met! ;-)