PTHPasteboard has problems in Lion. Copying less than a complete line from Safari, Mail, TextEdit, and iCal fails. Copying complete lines works as expected. I've noticed problems in other applications, but have not taken the time to test and confirm. I've had to restart it under Lion more often than under Snow Leopard.

I could not find any recent indications on the developer's site regarding plans to update. In early August I sent an inquiry to the developer concerning an update for Lion. I received no response after 4 days.

I've used PTHPasteboard Pro for about two years and rely on the filters, which are powerful functions and easy to set up. Unfortunately, it's now unreliable.