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DESCRIPTION
Geneious... Research software for biologists, not computer scientists.

Geneious combines all the major DNA and protein sequence analysis tools into one revolutionary software solution! Its ease of use makes bioinformatics accessible to any biologist. It even runs on all major operating systems and is very affordable.

Features include: Sequence alignment, Contig assembly, primers, restriction analysis, BLAST, phylogenetics, automatic publication updates and more.

WHAT'S NEW
Version 3.8.2:

New features added in Pro version only:

  • GenBank flat and XML exporters - For all nucleotide and protein sequences
  • Text view on GenBank documents - For sequences under 10K in length, the full GenBank flat record is provided as the text view
  • Vector screening - "Trim Ends" lets you trim for vector contamination
  • Support for sticky ends - restriction digest produces documents with sticky ends, and concatenation takes these into account
  • More sample restriction enzymes sets - Blunt, 3', 5' and common enzyme sets
  • Restriction analysis improvements - Find enzymes not cutting a sequence, and restrict the search for restriction sites to those that do not cut within a certain region
  • Extract annotations - inverse - You can extract all regions of a sequence not covered by an annotation

New features:

  • Sample NEB plasmids - Annotated plasmids from the NEB website are included in the sample documents
  • Concatenation into circular sequence - Concatenation can preserve the origin of a concatenated circular sequence fragment
  • Selected document count - status bar in document table informs you how many documents are selected
  • Go To Position in sequence - Jump to a particular index in a sequence, or select a particular range
  • Improvements to annotation rendering - New 3D look and other improvements
  • Performance improvements in the sequence/alignment viewer

Bugs fixed:

  • Go to next disagreement no longer prompts to save
  • Undo in the sequence/alignment editor no longer causes crashes
  • Primer design correctly evaluates all possible mismatches
  • Server database monitors external changes to documents being viewed
  • Many other small fixes
REQUIREMENTS
Mac OS X 10.4 or later, Java 1.5 or later.


SCREENSHOT

Developer:Biomatters Ltd.
Downloads:7,120
  - Version d/l:113
Education:Science
License:Free
Date:07 Jul 2008
Platform:PPC/Intel
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    Geneious User Reviews (1 post)Write A Review
    Aug 22 2006
    *****

    MIKENZ  For a long time scientists who generate or analyse DNA sequences have been using multiple pieces of software to: 1) view chromatographs, 2) trim sequences 3) Blast data 4) align sequences 5) build phylogenetic trees. Chopping and changing between different file formats and at times different operating systems (Mac, PC, Unix/Linux) has been a frustrating and time-consuming exercise. Current and future releases of Geneious (www.geneious.com) offer a solution to (most) of these frustrations. The software logo “research in a flash” accurately describe the potential of Geneious – only months after its release it has become the “Swiss army knife” of bioinformatics software.

    The user interface of Geneious is both attractive and intuitive. While the software has some “bell and whistles” for more complex tasks one of its key attributes is a simple user interface. Earlier this year I used the Beta-release in some undergraduate teaching labs – with great success. Students did a Genbank search, downloaded files, did an alignment and built a phylogenetic tree (with bootstrapping) all in the blink of an eye. If you are looking for a piece of bioinformatics software for teaching purposes look no further than Geneious.

    With the integration of sequence chromatograph viewing and editing of DNA sequences/alignments (new in version 2) Geneious is now firmly embedded in my research practices. As is the case with any new software there are a few features that don’t work quite as well as you might like – but the good news is that if you write to them they will likely fix it up asap. My request to provide a variety of nucleotide colour schemes was implemented within 2 weeks. Moreover, the software is structured in such a way that “new” plugins can be written and incorporated with relative ease.

    The Geneious team has made available a freeware version and a pro version that (for a price) allows you to access more functionality. Based on the hours of time this program has saved me already I would not even blink at the academic price tag of $133 (USD) – or cheaper for students.

    The software almost has too many features to comment on in any one review (e.g. “agents” and collaboration modes) - the best advice I can give is to download it, do the tutorial and test drive it on a bioinformatics task that you regularly conduct – it won’t disappoint.

    Cheers,  (Version 2.0.4)

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