Spark is a powerful and easy shortcuts manager. With Spark you can create Hot Keys to launch applications and documents, execute AppleScripts, command iTunes, and more...
You can also export and import your Hot Keys library, or save it in HTML format to print it.
FATFREDDYSCAT Short acquaintance as of yet, but so far it's working perfectly. Easy, fast, and to date rock solid. It amazes me that this is donationware; it's easily of the quality that could be sold commercially. Anyone interested in a hotkey manager absolutely should check this out, and donate if it proves to work as well for you as it does for me. (Version 3.0b8)